Automated cell type annotation and exploration of single-cell signaling dynamics using mass cytometry
Summary: Mass cytometry by time-of-flight (CyTOF) is an emerging technology allowing for in-depth characterization Card of cellular heterogeneity in cancer and other diseases.Unfortunately, high-dimensional analyses of CyTOF data remain quite demanding.Here, we deploy a bioinformatics framework that tackles two fundamental problems in CyTOF analyse